Recurrent partial hydatidiform mole.
نویسندگان
چکیده
Hydatidiform moles are abnormal conceptions characterised by atypical hyperplastic trophoblasts and hydropic villi. Their incidence is approximately 1 in 1000 pregnancies. The recurrence risk of hydatidiform mole is approximately 1 in 60 in a subsequent pregnancy and 1 in 6.5 in the third pregnancy. In cases with recurrence, the majority of moles are of the same type as that in the preceding pregnancy. Here, we describe the case of a recurrent partial hydatidiform mole after an initial healthy pregnancy. Both pregnancies were evacuated by suction curettage, and the patient was followed by serial monitoring of beta-human chorionic gonadotropin levels. Recurrent molar pregnancy is not an indication for chemotherapy, and subsequent pregnancies do not have an increased risk for other obstetric complications.
منابع مشابه
A Novel Mutation in NLRP7 Related to Recurrent Hyda-tidiform Mole and Reproductive Failure
Objective Hydatidiform mole (HM) is an abnormal human pregnancy with excessive trophoblastic proliferation and abnormal embryonic development, which is divided into two Complete (CHM) and Partial (PHM) groups. One subcategory of the CHMs is recurrent and familial, which is known as biparental hydatidiform mole (BiHMs) or recurrent hydatidiform mole (RHM). NLRP7 and KHDC3L, two maternal-effect g...
متن کاملWhich Is More Prominent in Recurrent Hydatidiform Mole, Ovum or Sperm?
Recurrent hydatidiform mole is defined as episodes of two molar pregnancies in a female. Often, complete moles onlyderive androgenic nuclear genome. We described two cases with repeated molar pregnancies attempted to preventfuture episodes by performing intracytoplasmic sperm injection (ICSI) and preimplantation genetic diagnosis (PGD)to assess genetic disorders. The first pat...
متن کاملThe pattern of benign gestational trophoblastic disease in Karachi.
A hospital based epidemiological study of benign gestational trophoblastic disease i.e., both complete and partial hydatidiform mole was undertaken at 8 hospitals. The frequency of the disease was found to be 3.89/1000 pregnancies and was found to be higher--1 in 237 deliveries in the economically deprived women admitted to a free Government Hospital, compared to only 1 in 471 deliveries in a P...
متن کاملNLRP7 or KHDC3L genes and the etiology of molar pregnancies and recurrent miscarriage.
Women with mutation in both alleles of the NLRP7 or C6orf221/KHDC3L genes are predisposed to diploid biparental moles, but it has also been suggested that mutation in these genes can predispose to diploid androgenetic or triploid moles and to other kinds of reproductive wastage. We have investigated the association between molar pregnancy and recurrent miscarriages regarding changes in the NLRP...
متن کاملGestational Trophoblastic Disorders: An Update
Gestational trophoblastic diseases (GTD) are a group of pregnancy-related disorders representing rare human tumours. They encompass premalignant disorders including complete (CHM), partial hydatidiform mole (PHM), exaggerated placental site (EPS), and placental-site nodule (PSN) as well as malignant disorders (also known as “gestational trophoblastic neoplasia [GTN]”) including invasive mole, c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- JPMA. The Journal of the Pakistan Medical Association
دوره 61 10 شماره
صفحات -
تاریخ انتشار 2011